🧬 GHK‑Cu: Research Overview

For Laboratory, Scientific, and Educational Research Only, COA,

GHK‑Cu (Glycyl‑L‑Histidyl‑L‑Lysine Copper Complex) is a naturally occurring copper‑binding peptide found in human plasma, saliva, and urine. In laboratory and preclinical research, it is widely studied for its roles in tissue remodeling, wound healing, gene expression, and cellular regeneration. Its ability to bind copper ions gives it unique biochemical properties that make it a prominent subject in regenerative and dermatological research.

⭐ Key Areas of Scientific Interest

Preclinical and mechanistic studies have explored GHK‑Cu for its potential involvement in:

Tissue Repair & Wound Healing

• Stimulation of collagen, elastin, and glycosaminoglycan production

• Support for fibroblast activity and extracellular‑matrix remodeling

• Acceleration of wound‑healing processes in experimental models

Anti‑Inflammatory & Antioxidant Activity

• Modulation of inflammatory cytokines

• Reduction of oxidative stress markers

• Interest in its role in protecting cells from environmental or chemical stressors

Skin & Hair Research

• Studies examining improvements in skin firmness, elasticity, and overall appearance

• Potential influence on hair‑follicle signaling pathways

• Research into age‑related changes in dermal structure

Gene Expression Modulation

• Regulation of hundreds of genes associated with repair, growth, and anti‑inflammatory pathways

• Downregulation of genes linked to oxidative stress and tissue breakdown

• Interest in its broad genomic influence in regenerative biology

Copper Transport & Cellular Function

• Delivery of bioavailable copper to cells

• Support for enzymatic processes dependent on copper ions

• Research into mitochondrial and metabolic pathways influenced by copper signaling